Latest publications

Displayed below is a list of the latest publications that have been added - in the last ten days -  to the library database of peer-reviewed journal articles arising from ESRF experiments, an RSS feed of this list can be subscribed to.

For the full list of publications, please visit the library web site.
 

New ESRF publications

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Discovery of clinical candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and optimization of diaryl ether aryl sulfonamides as selective inhibitors of NaV1.7

Swain Nigel. A., Batchelor D., Beaudoin S., Bechle B.M., Bradley P.A., Brown A.D., Brown B., Butcher K.J., Butt R.P., Chapman M.L., Denton S., Ellis D., Galan S.R.G., Gaulier S.M., Greener B.S., de Groot M.J., Glossop M.S., Gurrell I.K., Hannam J., Johnson M.S., Lin Z., Markworth C.J., Marron B.E., Millan D.S., Nakagawa S., Pike A., Printzenhoff D., Rawson D.J., Ransley S.J., Reister S.M., Sasaki K., Storer R.I., Stupple P.A., West C.W.,
Journal of Medicinal Chemistry 60, 7029-7042 (2017)

GSK6853, a chemical probe for inhibition of the BRPF1 bromodomain

Bamborough P., Barnett H.A., Becher I., Bird M.J., Chung C.W., Craggs P.D., Demont E.H., Diallo H., Fallon D.J., Gordon L.J., Grandi P., Hobbs C.I., Hooper-Greenhill E., Jones E.J., Law R.P., Le Gall A., Lugo D., Michon A.M., Mitchell D.J., Prinjha R.K., Sheppard R.J., Watson A.J.B., Watson R.J.,
ACS Medicinal Chemistry Letters 7, 552-557 (2016)

A chemical probe for the ATAD2 bromodomain

Bamborough P., Chung C.W., Demont E.H., Furze R.C., Bannister A.J., Che K.H., Diallo H., Douault C., Grandi P., Kouzarides T., Michon A.M., Mitchell D.J., Prinjha R.K., Rau C., Robson S., Sheppard R.J., Upton R., Watson R.J.,
Angewandte Chemie International Edition 55, 11382-11386 (2016)

Identification and in vivo evaluation of liver x receptor beta-selective agonists for the potential treatment of Alzheimer's disease

Stachel S.J., Zerbinatti C., Rudd M.T., Cosden M., Suon S., Nanda K.K., Wessner K., DiMuzio J., Maxwell J., Wu Z.H., Uslaner J.M., Michener M.S., Szczerba P., Brnardic E., Rada V., Kim Y., Meissner R., Wuelfing P., Yuan Y., Ballard J., Holahan M., Klein D.J., Lu J., Fradera X., Parthasarathy G., Uebele V.N., Zhong G.C., Li Y.J., Li J., Cooke A.J., Bennett D.J., Bilodeau M.T., Renger J.,
Journal of Medicinal Chemistry 59, 3489-3498 (2016)